News

A study reveals that NUDT5 regulates purine production, the process that builds DNA, without using its enzymatic activity. Instead, NUDT5 acts as a molecular scaffold that halts DNA synthesis when purine levels are high.

By employing a technique called Nanoendoscopy-AFM, which inserts a nanoneedle probe directly into cells, scientists revealed how cancer cell nuclei stiffen or soften depending on chromatin structure and environmental conditions.

Researchers from the Harvard T.H. Chan School of Public Health reveal new insights into how melanoma cells in lymph nodes survive by relying on FSP1, and how this could be targeted therapeutically.

New research has identified a molecular cascade that causes synaptic dysfunction that is shared by Alzheimer's and Parkinson's.

University of Michigan researchers discovered that touch can suppress a longevity gene called fmo-2 in worms, reducing the lifespan benefits of dietary restriction. The study reveals how sensory cues like texture can influence aging.

Researchers have uncovered a surprising role for the "Frazzled" protein in helping neurons connect and communicate in the brains of fruit flies.

Researchers found that intermittent fasting, when calorie intake remains unchanged, does not improve insulin sensitivity or other metabolic measures. Time-restricted eating shifted participants’ circadian rhythms.

Scientists from Bigelow Laboratory and Atrandi Biosciences developed a method called environmental microcompartment genomics that sequences thousands of individual microbes and viruses at once.

Immune cells actively shed a sugar coating to infiltrate inflamed skin, a mechanism linked to psoriasis and other inflammatory diseases.

Scientists from Duke-NUS Medical School and their collaborators have created one of the most comprehensive single-cell maps of the developing human brain.