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Model Predicts Drug Toxicity by Differences Between Preclinical Models and Humans
Discover how a machine-learning drug toxicity prediction model enhances the predictive power of AI in drug trials, boosting safety.
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Peanut Patch May Offer Lasting Protection for Toddlers With Peanut Allergy
Ongoing peanut patch treatment helps toddlers develop lasting tolerance while remaining safe, offering hope for families managing peanut allergies.
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Study Identifies Who Benefits from Schizophrenia Treatment
Study identifies which patients benefit most from new schizophrenia drug. It analyzed electronic medical records from 49 patients hospitalized for schizophrenia, schizoaffective disorder, or bipolar disorder with psychotic features.
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AI Model Accelerates Therapeutic Antibody Design
Researchers showed that a protein language model could design functional human antibodies that recognized unique antigen sequences of specific viruses, without requiring part of the antibody sequence as a starting template.
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Alzheimer's and Parkinson's Diseases Share Synaptic Dysfunction Mechanism
New research has identified a molecular cascade that causes synaptic dysfunction that is shared by Alzheimer's and Parkinson's.
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Molecular Movie Shows How Painkillers Trigger Opioid Receptors
Scientists have visualized for the first time how opioids such as loperamide and the antidote naloxone engage a key brain receptor, offering insight that could lead to better pain treatments.
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Common Acne Drug Linked to Lower Schizophrenia Risk
Researchers found that adolescents treated with the antibiotic doxycycline were ~30% less likely to develop schizophrenia as adults. The findings suggest that targeting brain inflammation could help reduce the future risk of severe mental illness.
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Nanoparticles Stimulate the Immune System To Attack Ovarian Tumors
By delivering an immune-stimulating molecule alongside immunotherapy, nanoparticles help the immune system attack ovarian tumors.
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Intermittent Fasting Changes Body Clocks Without Metabolic Gains
Researchers found that intermittent fasting, when calorie intake remains unchanged, does not improve insulin sensitivity or other metabolic measures. Time-restricted eating shifted participants’ circadian rhythms.
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New Compound Kills Cancer Cells by Blocking Waste Cleanup
New compound fragment disables cancer cells’ antioxidant defenses, paving the way for a next-generation treatment strategy that could work across multiple tumor types.
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