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Doctor presenting a virtual capsule for drug safety in clinical trials.
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Model Predicts Drug Toxicity by Differences Between Preclinical Models and Humans

Discover how a machine-learning drug toxicity prediction model enhances the predictive power of AI in drug trials, boosting safety.
A bowl of peanuts with shells in a bowl
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Peanut Patch May Offer Lasting Protection for Toddlers With Peanut Allergy

Ongoing peanut patch treatment helps toddlers develop lasting tolerance while remaining safe, offering hope for families managing peanut allergies.
Blue drug pill, half in as a circuit board, half with human brains - indicating drug discvoery.
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Study Identifies Who Benefits from Schizophrenia Treatment

Study identifies which patients benefit most from new schizophrenia drug. It analyzed electronic medical records from 49 patients hospitalized for schizophrenia, schizoaffective disorder, or bipolar disorder with psychotic features.
3D molecular model of a therapeutic antibody structure used in drug design and development.
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AI Model Accelerates Therapeutic Antibody Design

Researchers showed that a protein language model could design functional human antibodies that recognized unique antigen sequences of specific viruses, without requiring part of the antibody sequence as a starting template.
A synapse, with neurotransmitters passing through the synaptic cleft to receptors on the other side.
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Alzheimer's and Parkinson's Diseases Share Synaptic Dysfunction Mechanism

New research has identified a molecular cascade that causes synaptic dysfunction that is shared by Alzheimer's and Parkinson's.
Orange and white drug capsule with DNA in background.
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Molecular Movie Shows How Painkillers Trigger Opioid Receptors

Scientists have visualized for the first time how opioids such as loperamide and the antidote naloxone engage a key brain receptor, offering insight that could lead to better pain treatments.
The word schizophrenia highlighted in pink in a dictionary entry about psychotic disorders.
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Common Acne Drug Linked to Lower Schizophrenia Risk

Researchers found that adolescents treated with the antibiotic doxycycline were ~30% less likely to develop schizophrenia as adults. The findings suggest that targeting brain inflammation could help reduce the future risk of severe mental illness.
Immune cells attacking a cancer cell.
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Nanoparticles Stimulate the Immune System To Attack Ovarian Tumors

By delivering an immune-stimulating molecule alongside immunotherapy, nanoparticles help the immune system attack ovarian tumors.
Clock on a plate with utensils symbolizing the concept of intermittent fasting and meal timing.
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Intermittent Fasting Changes Body Clocks Without Metabolic Gains

Researchers found that intermittent fasting, when calorie intake remains unchanged, does not improve insulin sensitivity or other metabolic measures. Time-restricted eating shifted participants’ circadian rhythms.
Cancer cells infiltrating healthy cellular environment.
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New Compound Kills Cancer Cells by Blocking Waste Cleanup

New compound fragment disables cancer cells’ antioxidant defenses, paving the way for a next-generation treatment strategy that could work across multiple tumor types.
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