News

Researchers at the University of Bonn have uncovered how a kidney RNA molecule can trigger autoimmune disease. In mice, a mutation in the RIG-I immune receptor caused it to mistake kidney Y-RNA for viral RNA, leading to lupus-like inflammation.

Researchers found that brief hypoxia, experienced at altitude or during illness, reprograms bone marrow progenitors, creating neutrophils less effective at fighting bacteria. This epigenetic “memory” persisted for months in climbers after descent.

Some women undergo unnecessary mastectomy and chemotherapy, but a "labyrinth in a chip" could reveal which cancers need aggressive treatments.

Treatment for obesity in the UK could become a “two-tier system” where the most vulnerable patients miss out altogether.

University of Oslo scientists identified a panel of four microRNAs that can distinguish between heart failure types and healthy individuals. Two biomarkers are especially relevant for women, offering new precision tools for diagnosing heart failure.

A University of Michigan Health study finds that testing for TRIM63 overexpression in renal cell carcinoma can reveal previously undetected mutations, potentially opening the door to more treatment options for patients.

University of Connecticut chemists have created two fast, low-cost blood tests that detect microRNA markers linked to Alzheimer’s disease. Using CRISPR-Cas13A and luminescent dyes, the assays reveal early signs long before symptoms appear.

Chemists at Utrecht University have developed FibrilPaint, a fluorescent molecule that binds to amyloid fibrils, making it possible to measure the earliest protein clumps linked to Alzheimer’s and other dementias.

Researchers have identified gene activity changes in immune cells from blood samples that could enable early, non-invasive diagnosis and monitoring of Parkinson’s disease.

New research identifies why some cancer patients get heart damage during chemotherapy, offering hope for protecting the heart during treatment.