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ASO Drug Targets ALS and FTD Neuronal Hyperexcitability
Northwestern researchers were able to calm overactive neurons and restore neuronal activity, which could potentially slow the progression of disease.
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Antidepressant Fluoxetine Found To Rewire the Brain’s Energy System, Boosting Plasticity
New research reveals that the antidepressant fluoxetine does more than raise serotonin levels – it changes how brain cells use energy and rebuild their connections, potentially reopening the brain’s capacity to adapt.
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Obesity Care Divide Grows as Mounjaro Access Remains Limited
Treatment for obesity in the UK could become a “two-tier system” where the most vulnerable patients miss out altogether.
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GLP-1 Drugs Cut Weight Significantly, But Long-Term Data Limited
Three new Cochrane reviews find evidence that GLP-1 drugs result in clinically meaningful weight loss, but industry-funded studies raise questions.
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First Lab-Made Antivenom Protects Against Africa’s Deadliest Snakes
Scientists have co-developed the world’s first product-ready, lab-produced, recombinant snakebite antivenom that protects against many of Africa’s most dangerous snakes and outperforms existing antivenoms.
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Common Antidepressant Improves Core Depression Symptoms in Just Two Weeks
Sertraline contributes to a modest improvement in core depression and anxiety symptoms within two weeks, a new analysis has found.
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New Chemotherapy Agent LiPyDau Overcomes Drug-Resistant Cancer
Researchers have developed a groundbreaking new chemotherapeutic agent, LiPyDau, which shows remarkable efficacy against multiple tumor types in preclinical studies.
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Intracellular GPCR Targeting Unlocks New Biased Therapies
New study shows that targeting an oft-drugged family of cell membrane receptors with biased modulators can expand potential drug targets and reduce side effects.
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"Under-Appreciated" Gene Mutation Blocks Immune Checkpoint Inhibitors
An under-appreciated cancer mutation has been found to block immune checkpoint inhibitor drugs, offering a new approach to treating "cold" tumors.
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Raman Spectroscopy-Based Tool Monitors Vaccine Quality During Production
Enhancing continuous manufacturing of vaccines, researchers innovate a Raman spectroscopy tool for efficient quality control in production.
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