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Researchers have characterized the shape and structure of LNPs in unprecedented detail, revealing that the particles come in a surprising variety of configurations.

Attaching "fake targets" to tumor cells to guide immune cell attacks could overcome the limitations of conventional antibody-based therapies.

UCLA researchers have developed a CAR-NKT cell therapy that has been shown to be more effective than current immunotherapies at fighting cancer in tumor samples from late-stage triple-negative breast cancer patients.

A study reveals that mRNA vaccination near the start of immunotherapy nearly doubled survival in advanced lung and skin cancer patients.

The termination of thousands of federal grants that fund clinical trials threatens to reverse substantial progress in understanding and treating the health challenges of marginalized populations, particularly young adults.

Scientists have discovered how LINE-1, a “jumping gene” that makes up 17% of the human genome, inserts itself into DNA. Using advanced imaging, the team showed how the LINE-1 protein binds DNA and enables integration.

Researchers have engineered a rare type of immune cell to kill slow-growing bowel cancer cells that are resistant to current therapies.

Routine data from laboratories reveal a decline in vitamin D levels during the COVID-19 pandemic, especially in older women and urban dwellers.

Scientists developed an epigenetic editing platform using CRISPRoff and CRISPRon to reprogram human T cells. Unlike traditional CRISPR, this method avoids DNA cutting, enabling safe, simultaneous modification of multiple genes.

In pregnant women with sickle cell disease, the risk of developing early-onset preeclampsia can be determined by measuring levels of a protein associated with placental function and development.