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AI Model Accelerates Therapeutic Antibody Design
Researchers showed that a protein language model could design functional human antibodies that recognized unique antigen sequences of specific viruses, without requiring part of the antibody sequence as a starting template.
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Nanoprobe Microscope Maps Cancer Cell Flexibility
By employing a technique called Nanoendoscopy-AFM, which inserts a nanoneedle probe directly into cells, scientists revealed how cancer cell nuclei stiffen or soften depending on chromatin structure and environmental conditions.
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Electrochemical Biosensor Identifies Potential Lung Cancer Biomarkers
Researchers have developed biosensor technology that, when combined with artificial intelligence, shows promise for detecting lung cancer through breath analysis.
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Triggering Cell Death in Metastatic Melanoma May Pave the Way for New Cancer Treatments
Researchers from the Harvard T.H. Chan School of Public Health reveal new insights into how melanoma cells in lymph nodes survive by relying on FSP1, and how this could be targeted therapeutically.
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Toxic “Forever Chemicals” Found in British Columbia Sea Otters
Discover how scientists discovered PFAS in the bodies of sea otters in British Columbia, with otters near cities carrying triple the toxic load of more remote animals.
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Two Small Changes May Reduce Agriculture’s Dependence on Synthetic Fertilizers
Researchers have taken a major step toward understanding how certain plants can thrive without chemically produced nitrogen. A breakthrough that could eventually reduce the need for artificial fertilizers in crops such as wheat, maize, and rice.
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Targeting Macrophage "Bodyguards" Could Overcome Breast Cancer Treatment Resistance
A specific subtype of tumor-associated macrophage is more abundant in endocrine therapy-resistant tumors, and targeting these could improve treatment.
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Microglial Switch Identified That Protects Against Alzheimer’s Disease
Researchers have identified a unique microglial population that protects the brain by lowering inflammation and slowing amyloid and tau pathology.
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Climate Intervention May Not Be Enough to Save Coffee, Chocolate and Wine
Discover how even advanced climate intervention strategies may not be enough to secure the future of wine grapes, coffee and cacao harvests.
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Alzheimer's and Parkinson's Diseases Share Synaptic Dysfunction Mechanism
New research has identified a molecular cascade that causes synaptic dysfunction that is shared by Alzheimer's and Parkinson's.
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