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Latest App Notes & Case Studies

Papers from real-Time Metabolic Analysis in 3D Brain Models application note on a grey background.
App Note / Case Study

Real-Time Metabolic Analysis in 3D Brain Models

This app note highlights an optimized system for assessing mitochondrial respiration and glycolysis in brain tissue slices. It introduces a workflow that enables real-time, high-sensitivity metabolic profiling with consistent, reproducible results.
3D illustration of blue and white protein structures representing enhanced protein expression through Poly(A) innovation.
App Note / Case Study

Boost Protein Expression With Poly(A) Innovation

This technical note explores a novel poly(A) tail modification that enhances total protein expression and extends expression duration across multiple constructs and cap structures, without increasing immune response.
Scientist working with a single-use bioreactor system for advanced process development.
App Note / Case Study

Transform Process Development Efficiency With Single-Use Bioreactors

This application note explores how an advanced 5 L single-use bioreactor enhances productivity, reduces costs and enables seamless scalability from bench to production.
Scientist holding a blood sample tube for pTau 217 assay testing in Alzheimer’s research lab.
App Note / Case Study

An Innovative pTau 217 Assay Unlocks New Possibilities in Alzheimer’s Disease Research

This case study shows how a next-generation pTau 217 assay achieves higher accuracy than existing platforms using only 1 µL of diluted plasma, while maintaining robust performance across freeze-thawed samples and diverse cohorts.
Scientist examining a sample under a microscope in a forensic toxicology laboratory.
App Note / Case Study

Expand NPS Detection With High-Resolution Screening

This app note highlights a LC-MS/MS workflow that enhances NPS detection, enabling confident screening of over 900 compounds in complex biological matrices with a single injection.
An application note on reducing dsRNA during mRNA synthesis using novel RNA polymerase.
App Note / Case Study

Preventing Double-Stranded RNA Formation in mRNA Manufacturing

This application note highlights how a novel RNA polymerase provides a seamless solution that reduces dsRNA formation, minimizing the need for additional purification steps while maintaining superior mRNA quality and yield.
Colorful 3D rendering of a protein structure showing intricate folding and molecular detail.
App Note / Case Study

Leveraging Automation To Enhance Protein Analysis

This application note demonstrates how an automated parallel CE-SDS system can provide reliable measurements from 1 µL of protein crude lysate in just 30 minutes.
Agilent application note on spectral flow cytometry resolving overlapping fluorochromes.
App Note / Case Study

Unlock the Power of Spectral Flow Cytometry

This application note demonstrates how advanced spectral flow cytometry technology overcomes these limitations through sophisticated spectral unmixing algorithms, enabling researchers to distinguish fluorochromes with similar indices.
Bioluminescent imaging of mice comparing CleanCap AG, AG 3' OMe, and M6 mRNA expression levels
App Note / Case Study

Streamlined mRNA Capping Strategies for Enhanced Therapeutic Potential

This application note explores how these cutting-edge capping strategies enhance mRNA potency, stability and expression, providing valuable insights for researchers and manufacturers.
3D illustration of a DNA double helix intertwined with floating cells in a blue microscopic environment, representing genetic research and biotechnology
App Note / Case Study

Advanced Solutions for Accurate Cell-Free DNA Quality Assessment

This application note explores how electrophoretic methods surpass the capabilities of traditional methods to accurately distinguish between cfDNA and contaminating high molecular weight (HMW) DNA, making them ideal for cfDNA quality control.
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