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Healthcare worker drawing blood from a patient for immunological signature analysis.
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Understanding How Tuberculosis Affects the Body Beyond the Lungs

German researchers studying tuberculosis that spreads beyond the lungs identified unique immune patterns in patients’ blood. These patterns reveal how the body fights the infection and could lead to a simple blood test to replace biopsies.
3D molecular visualization of protein interactions representing proteomics and structural biology research.
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What the Human Protein Atlas v25 Brings to Disease Research

The Human Protein Atlas v25 offers expanded protein maps across blood, tissues and cells, adding structural and disease-linked data. With over 10 million annotated images, it enhances understanding of how proteins drive health and disease.
Medical illustration of drug-resistant, Mycobacterium tuberculosis bacteria
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Blood Test Could Detect Hidden Tuberculosis

Single-cell RNA sequencing identified distinct immune profiles in extrapulmonary TB, linking interferon–IL-1 signaling to disease progression and paving the way for blood-based diagnostics.
Diagram showing how leptin from obesity influences breast cancer cell metabolism, proliferation and migration.
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Fat Hormone Found To Activate Cancer-Promoting Metabolic Pathway

Researchers identified how leptin, a hormone from fat cells, fuels estrogen receptor-positive breast cancer. The study found leptin activates the enzyme SCD, boosting cancer cell growth and energy production.
A man holding a large stein of beer, outside.
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One Enzyme Could Be Behind Alcohol Addiction and Liver Disease

New research reveals that blocking an enzyme involved in fructose metabolism can reduce alcohol cravings and protect against liver damage.
Fluorescent microscopy image showing increased serotonin receptors in gut tissue after THC treatment.
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Low-Dose THC Eases HIV Drug Side Effects and Boosts Gut Health

Scientists found that long-term, low doses of THC reduced inflammation and liver toxicity caused by HIV and antiretroviral therapy. The treatment increased serotonin and healthy gut bacteria while lowering harmful bile acids.
Medical scan of human lungs highlighting abnormal tissue growth associated with lung cancer.
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Targeting Inflammation Could Halt Lung Cancer Before It Starts

Researchers used spatial transcriptomic mapping to reveal that inflammation drives the earliest stages of lung cancer. They identified highly inflamed regions containing tumor-associated cells.
Model of a human kidney showing blood vessels and internal structure.
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Mismatch Between Two Kidney Function Tests Signals Future Disease

New insights into kidney function tests suggest using creatinine and cystatin C together may lower the risk of kidney failure.
Gloved hand editing a DNA strand with tweezers, illustrating RNA-based genetic modification.
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Scientists Identify 117 Enzymes That Control Gene Transcription

Researchers uncovered 117 enzymes that modify RNA polymerase II, the key enzyme that transcribes DNA into RNA. The study revealed that even cell-surface kinases like EGFR act within the nucleus to regulate transcription.
Anatomical heart model on a desk with a doctor writing in the background, illustrating heart damage.
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Blood Test for Heart Damage Could Help Predict Dementia Risk

Higher midlife troponin levels predicted faster cognitive decline and greater dementia risk decades later, suggesting a simple blood test could help identify those at risk.
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